The Mu Variant

WHO says it is monitoring a new Covid variant called ‘mu’ The World Health Organization is monitoring a new coronavirus variant called “mu,” which the agency says has mutations that have the potential to evade immunity provided by a previous Covid-19 infection or vaccination. ......... Mu — also known by scientists as B.1.621 — was added to the WHO’s list of variants “of interest” on Aug. 30, the international health organization said in its weekly Covid epidemiological report published late Tuesday. .......... The variant contains genetic mutations that indicate natural immunity, current vaccines or monoclonal antibody treatments may not work as well against it as they do against the original ancestral virus, the WHO said. The mu strain needs further study to confirm whether it will prove to be more contagious, more deadly or more resistant to current vaccines and treatments. ........... Mu “has a constellation of mutations that indicate potential properties of immune escape,” the WHO wrote in its report Tuesday........ The agency is monitoring four variants “of concern,” including delta, which was first detected in India and is the most prevalent variant currently circulating in the U.S.; alpha, first detected in the U.K.; beta, first detected in South Africa, and gamma, first detected in Brazil. A variant of concern is generally defined as a mutated strain that’s either more contagious, more deadly or more resistant to current vaccines and treatments. ............. It’s also keeping a close watch on four other variants of interest — including lambda, first identified in Peru — that have caused outbreaks in multiple countries and have genetic changes that could make them more dangerous than other strains. ............ The new variant, mu, was first identified in Colombia but has since been confirmed in at least 39 countries, according to the WHO. Although the global prevalence of the variant among sequenced cases has declined and is currently below 0.1%, its prevalence in Colombia and Ecuador has consistently increased

Is the mu variant in California? What to know about the new WHO 'variant of interest'

WHO monitoring new coronavirus variant named Mu Health body says Mu, or B.1.621, first identified in Colombia, has been designated as a variant of interest ........ The Mu variant, also known as B.1.621, was added to the WHO’s watchlist on 30 August after it was detected in 39 countries and found to possess a cluster of mutations that may make it less susceptible to the immune protection many have acquired. ........ the Mu variant “has a constellation of mutations that indicate potential properties of immune escape”. Preliminary data suggests it may evade immune defences in a similar way to the Beta variant first discovered in South Africa ......... While the variant makes up less than 0.1% of Covid infections globally, it may be gaining ground in Colombia and Ecuador where it accounts for 39% and 13% of Covid cases respectively. ........... At least 32 cases of the Mu variant have been detected in the UK ....... most were found in London and in people in their 20s. Some of those testing positive for Mu had received one or two doses of Covid vaccine. ........ Part of the concern about Mu comes from the particular mutations it carries. One genetic change, the P681H mutation, is found in the Alpha variant first detected in Kent and has been linked to faster transmission. Other mutations, including E484K and K417N, may help the virus evade immunity defences, which could give the variant an advantage over Delta as immunity rises into the autumn.